Seneca Hotels

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Where to stay in Seneca?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Seneca on Hotels.com. These Seneca hotels consistently deliver on quality, location and traveller experience. Last updated on .

1. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (901 reviews)
This convenient Seneca hotel offers a complimentary morning meal, fitness centre, and free parking just 5 minutes from campus. Guests praise the attentive staff, while Littlejohn Coliseum and Sloan Tennis Centre are located nearby.
The price is S$143
includes taxes & fees
19 Nov - 20 Nov
Tru by Hilton Seneca Clemson

2. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (764 reviews)
Just 5 minutes from Lake Keowee, this hotel offers a 24-hour fitness centre and seasonal outdoor swimming. Enjoy complimentary breakfast, WiFi, and parking while staying close to Clemson University. Guests consistently praise the helpful staff and clean accommodation.
The price is S$175
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites Seneca-Clemson Area

3. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.2 out of 10, Wonderful, (289 reviews)
Minutes from Clemson University and Lakes Keowee and Hartwell, this Seneca hotel offers free breakfast and parking. Refresh at the outdoor pool or fitness centre after exploring nearby Golden Corner Plaza and Gignilliat Community Centre.
The price is S$169
includes taxes & fees
8 Nov - 9 Nov
Fairfield Inn & Suites Seneca Clemson Univ Area

4. Quality Inn Seneca US-123

Quality Inn Seneca US-123
2.5 star property
Seneca
8.0 out of 10, Very good, (766 reviews)
Serene hotel within a 15-minute drive of Clemson University offers a seasonal outdoor pool, complimentary WiFi, parking, and breakfast. Toy Train Park and The Gauntlet attractions are nearby, with guests consistently praising the quiet atmosphere and attentive service.
The price is S$127
includes taxes & fees
6 Nov - 7 Nov
Quality Inn Seneca US-123

5. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,000 reviews)
Unwind at this lakeside retreat with a poolside bar and seasonal outdoor pool just minutes from Clemson University. The 24-hour fitness centre and hot tub provide recreation options while the restaurant and lounge offer on-site dining convenience.
The price is S$173
includes taxes & fees
2 Nov - 3 Nov
Lakeside Lodge Clemson

6. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (697 reviews)
Located within a 10-minute drive of Clemson University, this Seneca hotel offers a seasonal outdoor pool and free daily breakfast. Guests appreciate the helpful staff and clean rooms, while enjoying convenient access to local attractions.
The price is S$136
includes taxes & fees
30 Nov - 1 Dec
Best Western Seneca-Clemson

7. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, Good, (792 reviews)
This Seneca motel offers easy access to Clemson University and Lake Keowee. Take a refreshing dip in the seasonal outdoor pool after exploring nearby Lake Hartwell. Free WiFi, parking, and daily on-the-go breakfast add exceptional value.
The price is S$106
includes taxes & fees
30 Nov - 1 Dec
Days Inn by Wyndham Seneca / Clemson Area

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (116 reviews)
Tucked between Lake Hartwell and Lake Keowee, these charming cabins offer serene patios and well-equipped kitchenettes. Just minutes from outdoor recreation areas and Cross Creek Plantation Golf, with free parking and cosy climate control for year-round comfort.
The price is S$175
includes taxes & fees
30 Nov - 1 Dec
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

9. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
Clemson
8.8 out of 10, Excellent, (652 reviews)
Unwind at this well-positioned hotel near Larry W. Abernathy Waterfront Park, offering a seasonal outdoor pool for morning swims. Free breakfast, WiFi, and parking await, with Clemson Station just a 19-minute walk away.
The price is S$156
includes taxes & fees
7 Nov - 8 Nov
Hampton Inn Clemson-University Area

10. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (657 reviews)
Experience Southern hospitality at this refined Clemson hotel just minutes from campus attractions. Unwind with a cocktail at the stylish bar after exploring nearby Sloan Tennis Centre and Littlejohn Coliseum. Free parking and convenient location make this an ideal collegiate getaway.
The price is S$216
includes taxes & fees
22 Nov - 23 Nov
The Abernathy of Clemson

11. Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (591 reviews)
This business-friendly spot near Clemson Area African American Museum features American cuisine at The Bistro, plus a fitness centre and bar. Enjoy free WiFi and parking while staying close to South Carolina Botanical Gardens.
The price is S$147
includes taxes & fees
22 Nov - 23 Nov
Courtyard Marriott Clemson

12. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (903 reviews)
Moments from Lake Hartwell, this hotel blends walkable access to campus with comfort. Enjoy attentive service, a welcoming restaurant, and stylish bar where you can unwind. Just a 13-minute walk from Clemson Station connects you to broader adventures.
The price is S$297
includes taxes & fees
31 Oct - 1 Nov
The Shepherd Hotel Downtown Clemson

13. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (1,005 reviews)
Set on the grounds of Clemson University, this welcoming hotel offers direct access to Walker Golf Course, a seasonal outdoor pool, and poolside bar. Enjoy American cuisine at Sole on the Green or squeeze in a workout at the 24-hour fitness centre while exploring campus.
The price is S$197
includes taxes & fees
30 Nov - 1 Dec
Clemson University's James F. Martin Inn

14. Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very good, (1,010 reviews)
Take advantage of the complimentary breakfast, WiFi and parking at this hotel near Lake Hartwell and Clemson University. Guests praise the helpful staff, clean rooms and quiet environment. The fitness centre adds value for active travellers.
The price is S$106
includes taxes & fees
2 Nov - 3 Nov
Inn @ Clemson

15. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (998 reviews)
Minutes from Clemson University and Lake Hartwell, this hotel offers complimentary WiFi, parking, and breakfast. Work out in the fitness centre before exploring nearby attractions like the African American Museum and waterfront park.
The price is S$183
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Clemson by IHG

16. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.4 out of 10, Very good, (1,002 reviews)
Take a dip in the seasonal outdoor pool at this Clemson hotel, just a 15-minute drive from Clemson University. Enjoy free breakfast, parking, and fitness centre access, with African American Museum and Waterfront Park nearby.
The price is S$144
includes taxes & fees
29 Nov - 30 Nov
Comfort Inn & Suites Clemson - University Area

17. Econo Lodge Clemson - University Area

Econo Lodge Clemson - University Area
2.0 star property
Clemson
7.2 out of 10, Good, (160 reviews)
Wake up refreshed at this convenient Clemson hotel, just a 5-minute drive from the university. Free WiFi and parking make campus visits easy, while nearby attractions like the African American Museum offer cultural exploration. The 24-hour front desk ensures assistance anytime.
The price is S$109
includes taxes & fees
26 Nov - 27 Nov
Econo Lodge Clemson - University Area

18. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
Walhalla
7.6 out of 10, Good, (199 reviews)
Wake up to complimentary continental breakfast at this welcoming Walhalla motel. Located near Art Circle Gallery and Goldfish Pond, the property offers free WiFi and parking. Just a 22-minute drive from Clemson Station for easy regional exploration.
The price is S$114
includes taxes & fees
29 Nov - 30 Nov
Rodeway Inn & Suites Walhalla

19. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.0 out of 10, Very good, (1,004 reviews)
Walking distance from Clemson Station, this welcoming hotel sits just 5 minutes from the university campus. After a free breakfast, cool off in the seasonal outdoor pool or hit the 24-hour fitness centre. Nearby attractions and quiet, comfortable rooms await.
The price is S$144
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Clemson Hotel & Conference Center

20. Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.6 out of 10, Exceptional, (10 reviews)
Experience cosy comfort in this well-appointed cottage featuring a full kitchen and washer/dryer. Just 5 minutes from Clemson University and Lake Hartwell, with free WiFi and parking. The balcony offers a perfect spot to unwind after exploring nearby South Carolina Botanical Gardens.
The price is S$304
includes taxes & fees
1 Nov - 2 Nov
Clemson Memorabilia House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Check out pet-friendly hotels in Seneca

You can also stay at hotels with a pool in Seneca

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Seneca?

Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveller single night rates
View properties in October
Currently viewing crowd sizes and weather for October.
Typical weather for Seneca
October
High 23°C / low 12°C. Sunny most days.
View properties in October
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October, no crowd data, average high temperature 23 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
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December, no crowd data, average high temperature 12 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
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January, no crowd data, average high temperature 10 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
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February, no crowd data, average high temperature 13 degrees Celsius, average low temperature 3 degrees Celsius. Partly sunny.
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March, no crowd data, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
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April, no crowd data, average high temperature 22 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 26 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top neighbourhoods in Seneca

Downtown

City centre Seneca charms visitors with well-preserved historical buildings that tell the storey of its railway heritage. The tree-lined Ram Cat Alley showcases local history through colourful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodation range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire city centre is walkable with wide pavements, making it easy to discover this authentic slice of small-town America at your own pace.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Holiday rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The area trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront holiday homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This area is all about authentic lakeside living without commercial distractions. Most travellers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy area in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in holiday rental homes with private yards and driveways. The area gets incredibly quiet after dark—ideal for travellers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic city centre offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

A sunset over a lake surrounded by dense forests and residential areas.

Check out reviews of Seneca hotels guests love

Frequently asked questions

Can I book a refundable accommodation option in Seneca?
If you want the flexibility to change your plans to Seneca, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a holiday rental instead of a hotel?
If you want a good alternative to a hotel, browse our selection of 217 holiday homes. In addition, there are 24 apartments and 13 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August, with an average temperature of 25°C. January and February are the chilliest months, when the average temperature is 8°C. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.