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Cayo Santa Maria Hotels

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Search for hotels in Cayo Santa Maria

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Where to stay in Cayo Santa Maria

What's Cayo Santa Maria like?

If you're looking to discover somewhere new, look no further than Cayo Santa Maria. Whether you're planning to stay for a night or for the week, the area around Cayo Santa Maria has accommodations to fit every need. Search for hotels in Cayo Santa Maria with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Cayo Santa Maria hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Cayo Santa Maria hotel deals are here with our lowest price guarantee.

Where are the best places to stay in Cayo Santa Maria?

We have 13 Cayo Santa Maria accommodations. Choose one of our 67 deals and get discounts of up to 55%.

Below are the number of accommodations by star rating in Cayo Santa Maria and the surrounding area:

  • • 6 4-star accommodations
  • • 3 3-star accommodations

Here are our travelers' top 3 places to stay in Cayo Santa Maria:

Valentin Perla Blanca - Adults Only

Adults-only hotel on beach
  • • Free parking • 4 beach bars • 7 restaurants • 2 outdoor pools • Central location

Ocean Casa Del Mar - All Inclusive

Cayo Santa Maria beachfront property with 9 bars, free children's club
  • • Free breakfast • Free parking • 9 restaurants • 2 outdoor pools • Walkable location

Grand Memories Santa Maria - All Inclusive

All-inclusive beachfront property with free children's club
  • • Free breakfast • Free parking • 5 restaurants • Beach bar • Outdoor pool

When is the best time to visit Cayo Santa Maria?

  • • Hottest months: August, July, September, June (average 87°F)
  • • Coldest months: February, January, March, December (average 60°F)
  • • Rainiest months: September, August, October, and July (average 7.00 inches of rainfall)